fluorofenidone相关论文
Microcarrier as pulmonary drug delivery system for treatment of pulmonary fibrosis induced by paraqu
It has been shown that endoplasmic reticulum stress (ERS) is involved in the pulmonary fibrosis.Fluorofenidone (AKF) is ......
In vitro inhibition and induction of human liver cytochrome P450 enzymes by a novel anti-fibrotic dr
Aim: The main aim of this study is to evaluate the ability of Fluorofenidone to inhibit and induce human cytochrome P450......
Surface sperimidine functionalized, fluorofenidone-loaded PEG-PLGA nanoparticles for enhanced treatm
Despite significant efforts have been made to prevent paraquat (PQ)-induced pulmonary fibrosis,including corticosteroids......
器官纤维化可发生于不同的组织器官,其发病率高、危害性大,尚缺乏有效的治疗药物。近年发现的新型抗纤维化小分子化合物——氟非尼......
目的:探讨氟非尼酮(fluorofenidone,AKF-PD)对内皮素-1(endothelin-1,ET-1)诱导的肝星状细胞(hepatic stellate cell,HSC)收缩的影响及对......
以固态反应制得氟非尼酮的光聚合产物,使用制备色谱分离纯化,通过UV、MS、13C NMR、1H-1H COSY、HMBC、HMBQ对其进行结构确证。建......