mitochon相关论文
白色念珠菌是目前最常见的共生真菌,在免疫功能低下的个体中很容易引起侵袭性真菌感染.茶皂素(TS)是一种安全的天然产物,已有报道......
目的 研究氟斑牙大鼠是否可能发生软组织肿瘤,以及瘤组织中内质网应激和线粒体凋亡途径中关键基因的转录水平.方法 SD大鼠20只,饮......
Mitochondrial division inhibitor 1 protects cortical neurons from excitotoxicity: a mechanistic path
Mitochondrial division inhibitor 1 (Mdivi-1) is a selective cell-permeable inhibitor of dynamin-related protein-1 (Drp 1......
Essential Oil from Siegesbeckia pubescens Induces Apoptosis through the Mitochondrial Pathway in Hum
Siegesbeckia pubescens (SP) has been used as a traditional medicine for the treatment of and inflammatory diseases.Howev......
The cytotoxic effect of nitric oxide on primarily cultured rat cerebellar granule cells was stuatea, and the mechanisms......
Retinal ganglion cells in the rat were studied using the heavy metal intensified cytochrome oxidase and horseradish pero......
The family of glutathione peroxidases encompasses, as far, three tetrameric glutathione’peroxidases (GPx) and the monom......
Objective To investigate the antitumor effect of chabamide in K562(human leukemia cell line) cells. Methods The cytotoxi......
AIM: To investigate the effect of Ginkgo biloba extract on the enteric neurons in the small intestine of diabetic rats. ......
Saeng-Kankunbi-Tang(生肝健脾汤) Protects Liver against Oxidative Damage through Activation of ERK/Nrf2 Pa
Objective: To investigate the cytoprotective effects of Saeng-kankunbi-tang(生肝健脾汤, SKT), a herbal prescription cons......
The existence and characteristics of nitrate reductase (NR) have been investigated with microsomes and purified plasma m......
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neur
Alzheimer’s disease (AD) is a progressive neurodegenerative disease leading to the irreversible loss of brain neurons a......
,The role of RIP3 in cardiomyocyte necrosis induced by mitochondrial damage of myocardial ischemia-r
Myocardial damage caused by myocardial ischemia-reperfusion injury (MIRI) is difficult to be alleviated because cardiomy......
,A peep into mitochondrial disorder: multifaceted from mitochondrial DNA mutations to nuclear gene m
...
Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral m
Mitochondrial dysfunction is the key pathogenic mechanism of cerebral injury induced by high-altitude hypoxia. Some Chin......
目的 探讨电离辐射诱导人淋巴细胞线粒体COX Ⅰ、COXⅡ和COXⅢ基因表达的改变.方法 用1、3、5、8和10 Gy 60Co γ射线分别照射指数......
线粒体是心肌保护的重要靶器官。随着对缺血再灌注损伤的机制研究的深入，线粒体ATP敏感性钾通道的开放和线粒体通透性转化孔的关闭......
沉默交配型信息调节因子2同源蛋白3(SIRT3)是Sirtuins脱乙酰基酶家族中的一员,是酵母沉默信息调节因子2的同源物,是一种依赖于烟酰......
Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral m
Mitochondrial dysfunction is the key pathogenic mechanism of cerebral injury induced by high-altitude hypoxia. Some Chin......
The linkage between Qi and mitochondria was investigated by exploring the effect of Traditional Chinese Medicine (TCM) Q......
为了揭示紫外线诱导桃蚜的生态学及分子变异的遗传效应,以在正常环境中生长的桃蚜为对照,研究了紫外线不同辐射强度（15,30,45 W）和时......
目的:探讨常规冷停搏液ST.Thomas,人参总皂甙及人参皂甙Rb三种保护液对缺血再灌注心肌损伤的保护效果.方法:对每一例患者手术中阻......
本文用低硒饲料(硒含量0.009mg/kg)和低硒饲料补亚硒酸钠(硒含量0.232mg/kg)分别喂养大鼠,对比观察喂养1,2和3个月时两组大鼠心肌......
目的研究左旋多巴(L-dopa)对帕金森病(PD)模型大鼠异常行为、黑质抗氧化系统、线粒体呼吸链功能和神经递质代谢的影响及其机制.方......
目的探讨益肺汤联合线粒体辅酶Q(MitoQ)对生长转化因子(TGF-β1)诱导的人肺泡上皮细胞HPAEpiC间质转化的抑制作用。方法选择细胞株......
心功能不全合并脓毒症导致重症监护室(ICU)患者的病死率增高。目前,心功能不全合并脓毒症的临床治疗方法通常是延缓心力衰竭并联合......
采用ＰＣＲ－ＳＳＣＰ、ＰＣＲ－ＲＦＬＰ及ＰＣＲ产物直接则序等技术对ＮＩＤＤＭ（即非胰岛素依赖型糖尿病）及８０例正常对照个体的血细胞线粒体ＤＮＡ进行了突变分析。结果天２例患者中发现线粒体......
目的初步探讨解偶联蛋白2（UCP2）在PM2.5致心肌细胞损伤中的作用。方法培养大鼠心肌细胞株H9C2细胞,给予si RNA和（或）PM2.5刺激,48h后检......
研究啤酒花（Humulus Lupulus L．）中成分异葎草酮（tetrahydro-iso-α-acid）对人胃腺癌细胞SGC-7901和人肝癌细胞HepG-2的体外抑制作用，并......
线粒体ND6基因（MT-ND6）上的m.14484T＞C突变是Leb er＇s遗传性视神经病变（Leber＇s hereditary optic neuropathy,LHON）的一个原发性突变,但......
【目的】研究高温和氧化应激对体外培养肉鸡骨骼肌线粒体功能的影响，初步探讨高温影响肉鸡肌肉品质的机制。【方法】从16只2周龄AA......
采用滚环复制和两步长PCR扩增相结合的方法,成功测出武昌罗索线虫Romanomermis wuchangensis线粒体基因组全序列。序列的注释和分......
本文报导1例Ⅲ型Joseph病黄氏家系患者腓肠肌活检的组织化学观察结果,表明NADH—TR反应增强,而SDH反应减弱,提示线粒体的酶反应出......
目的:研究针刺对大负荷运动大鼠骨骼肌线粒体结构与功能的影响,探讨针刺干预对运动性骨骼肌损伤的恢复和预防的作用。方法:128只成......
目的：观察缺氧对血管内皮细胞[Ca^2＋]i和线粒体膜电位的变化及金钠多的保护作用。方法：血管内皮细胞分为6组，用激光共聚焦显微镜测量各......
目的探讨PCR-变性高效液相色谱（PCR-DHPLC）分析技术在检测线粒体（mt）12S rRNA基因第1555位A-G均质点突变中的应用。方法 4例临床诊断为......
目的探讨灵芝对大鼠脑缺血再灌注后神经细胞凋亡率及线粒体跨膜电位的影响。方法采用线栓阻断大脑中动脉闭塞法（MCAO）建立大鼠局灶性......
目的：探讨中药半枝莲提取物（Scutellaria Barbata extract,ESB）含药血清对肝癌H22细胞凋亡率及线粒体膜电位的影响。方法：体外培养小鼠......
目的 观察 PPENK-MIDGE-NLS基因载体对大鼠心肌缺血再灌注时线粒体的影响.方法 成 年 雄 性 S D大 鼠 40 只,随机分为假手术组（开胸......
A study on mitochondrial respiratory dysfunction and lipid peroxidation in the liver after radiation
Male mice were subjected to 6 Gy total body irradiation,20% TBSAfull-thickness burns,or combined radiation-burn injury a......
目的人类热性惊厥多发生于6个月～5岁的儿童.小儿热性惊厥的发生率随体温上升明显升高,惊厥发生时体温为38.0～42℃.但是热性惊厥的病......
Leigh综合征是由于线粒体呼吸链能量代谢障碍所导致的遗传性疾病,呼吸链酶复合物I缺陷是导致Leigh综合征的常见原因之一。该研究通......
采用不同浓度的NdCl3营养液,对中国蕙兰进行根、叶表面喷施培养,分析了蕙兰根部线粒体抗氧化酶SOD、呼吸代谢酶COX活性及同工酶的......
为研究白藜芦醇（Resveratrol，RES）处理对猪孤雌激活囊胚抗冻能力的影响，利用2μmol／LRES在卵母细胞体外成熟、玻璃化冷冻与解冻和随后的......
目的:研究羟基喜树碱是否可通过线粒体途径诱导人肝癌细胞SMMC-7721凋亡.方法:将不同浓度的羟基喜树碱作用于肝癌细胞SMMC-7721,用......
用分离纯化的完整线粒体和部分细胞器组分，初步研究了脱辅基细胞色素ｃ在细胞内转运的特异性，完整线粒体用差速离心和密度梯度离心的方......
应用电子显微镜对正常条件下饲养的０￣１６日龄粘虫Ｍｙｔｈｉｍｎａ ｓｅｐａｒａｔａ（Ｗａｌｋｅｒ）雌蛾飞行肌超微结构的研究结果表明：肌原纤维直径、线粒体和横管的体积分量均随蛾龄的......
目的研究葛根素对匹罗卡品诱导癫痫大鼠海马神经元的保护作用及其可能机制。方法随机将30只成年雄性Wistar大鼠均分为5组:对照组、......
目的构建用于线粒体DNA（mtDNA）D-环控制区（D—LOOP区）多态性多个位点集成检测的寡核苷酸芯片。方法根据GenBank中人mtDNA D—LOOP区序......
根据位点特异性频率模型（site-specific rate model）,利用PAUP软件,对线粒体COI基因序列不同密码子位点的数据模块分别进行了豉甲科......
