n-terminal相关论文
N2L,a novel lipoic acid-niacin dimer,attenu⁃ates ferroptosis and decreases lipid peroxida⁃tion in HT
OBJECTIVE N2L is a novel lipoic acid-niacin dimer regulating lipid metabolism with multifunction,including antioxidant e......
目的 评价重症监护病房(ICU)危重患者血清N末端B型利钠肽(NT-proBNP)水平升高对住院30 d死亡风险的影响.方法 采用回顾性研究方法,......
制备氨基末端定点PEG修饰的尿酸酶,并比较尿酸酶修饰前后的免疫原性差异。采用M_r 20k的mPEG-丙醛选择性修饰尿酸酶的氨基末端;利......
目的 探讨N末端脑钠肽前体(NT-proBNP)联合新生儿危重病例评分(NCIS)对极低出生体质量儿(VLBWI)死亡风险的评估价值.方法 对2011年......
目的 探讨血浆氨基末端B型脑钠肽前体(NT-proBNP)在急性呼吸窘迫综合征(ARDS)诊断、严重程度及预后评估中的应用价值.方法 比较50......
所述的N-末端糖氨基酸是糖与氨基酸的氨基末端相连接。所设计的N-末端糖氨基酸类似物经保护,骨架合成,缩合和脱保护的步骤合成。进一......
目的探讨川崎病(KD)患儿血浆N末端脑利钠肽前体(NT-proBNP)和脑利钠肽(BNP)变化及其意义。方法采用ELISA分别测定51例KD患儿应用IVIG前、......
目的筛选可与HIV-1 gp41 NHR结合的环肽,为研制抗HIV-1早期感染的小分子药物奠定基础。方法采用P+LS方法,用源于gp41 NHR的合成肽N......
目的:探讨血浆N末端-脑钠肽前体(NT-proBNP)水平与不稳定型心绞痛(UAP)患者近期预后的关系。方法:因胸痛住院并经冠状动脉造影检查确诊为......
The risk of hepatocellular carcinoma(HCC) development increases as hepatitis virus C(HCV)-related liver diseases progres......
c-Jun N-terminal kinase-mediated Rubicon expression enhances hepatocyte lipoapoptosis and promotes h
AIM: To clarify the relationship between autophagy and lipotoxicity-induced apoptosis, which is termed 'lipoapoptosi......
目的 探讨急性左心衰竭、二尖瓣狭窄伴急性肺水肿与循环N端脑钠肽前体(NT-pro BNP)的关系。方法 收集2013年1月~2016年1月因急性左心......
短肽及胰岛素的N-末端经Dixpn转氨后具有荧光发色性质,其激发与发射波长随肽链氨基酸残基的种类和数量的不同而有差异,其范围大约......
目的探讨血浆氨基末端脑钠肽前体(N-terminal pro-brain natriuretic peptide,NT-proBNP)水平与新生儿危重病例评分法(NCIS)分值的......
目的 探讨血清N末端脑钠肽前体(NT-pro BNP)和降钙素原(PCT)水平在脓毒症患者中的表达水平及相关性。方法 采集120例脓毒症患者和40例......
目的探讨慢性心力衰竭(CHF)患者外周血半乳糖凝集素(Gal)-3、N末端B型利钠肽原(NT-proBNP)表达水平的变化。方法选择89例CHF患者作为研究......
Voltage-gated potassium channels comprise 12 subtypes (Kv1-Kv12). Kv2.1, which is expressed in most mammalian central ne......
心力衰竭(Heart Failure,HF)是一种常见的急性或慢性心血管危重症,近年来有年轻化趋势。由于早期HF常无临床表现,且目前对于HF的诊断一......
原发性高血压(EH)是受多基因遗传、多环境因素影响的代谢紊乱综合征,EH患者常出现左室肥厚(LVH),渐而出现舒张功能不全,乃至全心衰竭,早期......
目的观察衍生自人Ⅱ型磷脂酶A2(PLA2)N-端的多肽hPLA2N1-11对不同细菌在体外的杀菌效应。方法根据人ⅡA型PLA2 N-端11个氨基酸残基的......
利钠肽(BNP)主要由心室肌合成和分泌,当心室容量和压力负荷增加时,心肌受到牵张,心肌细胞内储存的proBNP即被释放出来,并很快分解......
Patients with pulmonary embolism (PE) have a high risk of death and it is important to recognize factors associated with......
Signal Transduction Pathways Mediated by Secreted and Non-Secreted Forms of Intact Insulin-Like Grow
Our previous results indicated that both the secreted and the intracellular form of full length and 1-97 N-terminal frag......
Diagnostic Value of Combined Detection of Galectin-3 and N-Terminal B-Type Natriuretic Peptide in Pa
Background: Acute heart failure timely and effective diagnosis and treatment directly affects the prognosis of patients,......
The P22 phage system is an intensely studied model system. Studies have ranged from biochemical analysis of basic life p......
AIM:To investigate whether tumor necrosis factor-α(TNF-α)mediates ischemia-reperfusion(I/R)-induced intestinal mucosal......
The number of patients with nonalcoholic fatty liver diseases(NAFLD)including nonalcoholic steatohepatitis(NASH),has bee......
Retrospective Study Clinical presentation and early predictors for poor outcomes in pediatric myocar
BACKGROUND Myocarditis is an important cause of morbidity and mortality in children, leading to long-term sequelae inclu......
Effect of milrinone on the cardiac function and N-terminal pro-brain natriuretic peptide levels in p
Objective:To study the effect of milrinone on the cardiac function and N-terminal pro-brain natriuretic peptide (NT-proB......
In order to establish the sequence dependence of RimJ-mediated protein N-terminal acetylation in E. coli, the Z-domain v......
Plasma N-terminal pro-brain natriuretic peptide levels in elderly patients with isolated diastolic d
To investigate plasma N-terminal pro-brain natriuretic peptide (NT-BNP) levels and to assess their clinical significance......