报告先天性甲肥厚1个家系,2代共有3人患病,3例患者均有甲增厚、掌跖角化、掌跖多汗,局部摩擦可发生水疱和毛发稀疏等典型表现.先证......

患者男，18岁。甲及掌跖部皮损18年。皮损特征表现为：20甲高度增厚、掌跖部严重角化、毛囊角化，尤以肘膝部明显、乳头角化及面部多发性......

Pachyonychia congenital (PC), consist of a group of rare autosomal-dominant ectodermal disorders. Symmetrically thickene......

Here we report a family with a clinical spectrum of Pachyonychia Congenita Tarda (PCT) encompassing two generations via ......