pluripotent相关论文
Heat shock protein 20 promotes sirtuin 1-dependent cell proliferation in induced pluripotent stem ce
BACKGROUND Heat shock proteins(HSPs)are molecular chaperones that protect cells against cellular stresses or injury.Howe......
Drug-induced pancreatitis is a gastrointestinal adverse effect concerning about 2%of drugs.The majority of cases are mil......
Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem ce
Mesenchymal stem cells(MSCs)have received significant attention in recent years due to their large potential for cell th......
HDAC6 is critical for ketamine-induced impairment of dendritic and spine growth in GABAergic project
Ketamine is widely used in infants and children for anesthesia;both anesthetic and sub-anesthetic doses of ketamine have......
The success achieved over the last decade with islet transplantation has intensified interest in treating diabetes,not o......
Induced neural stem/precursor cells for fundamental studies and potential application in neurodegene
Recent research has shown that defined sets of exogenous factors are sufficient to convert rodent and human somatic cell......
Stem cells represent a promising step for the future of regenerative medicine. As they are able to differentiate into an......
Progressively loss of neural and glial cells is the key event that leads to nervous system dysfunctions and diseases. Se......
Hepatocyte selection medium eliminating induced pluripotent stem cells among primary human hepatocyt
Hepatic insufficiency is a fatal liver disease with a significant decrease in functioning hepatocytes. If hepatocytes co......
Cell therapy from bench to bedside:Hepatocytes from fibroblasts-the truth and myth of transdifferent
Hepatocyte transplantation is an alternative to liver transplantation in certain disorders such as inheritedliver diseas......
The existing mismatch between the great demand for liver transplants and the number of available donor organs highlights......
Application of human bone marrow-derived mesenchymal stem cells in the treatment of radiation-induce
Nuclear accidents and terrorism present a serious threat for mass casualty.Accidental or intended radiation exposure lea......
<正>Stem cells are a group of multipotent or pluripotent cells which could differentiate into specialized cells or could......
A growing body of literature has shown that stem cells are very effective for the treatment of degenerative diseases in ......
Comparative pluripotency analysis of mouse embryonic stem cells derived from wild-type and infertile
Therapeutic cloning, whereby embryonic stem cells (ESCs) are derived from patient-specific cloned blastocysts via somati......
又到了Science Watch对热点研究进行年度回顾的时刻。根据2009-2011年所发表的论文在2011年获得的引用次数,表1列出了最具影响力作......
Regenerative medicine,including cell-replacement strategies,may have an important role in the treatment of type 1 diabet......
If only at a small scale,islet transplantation has successfully addressed what ought to be the primary endpoint of any c......
2012年10月8日获得诺贝尔生理学或医学奖的两位科学家为再生医学奠定了基础。再生医学即利用自体细胞产生的组织重建机体,至今仍是......
Mesenchymal stem cells(MSCs) derived from human induced pluripotent stem cells(hiPSCs) provide a novel source for genera......
Periosteum is a thin fibrous layer that covers most bones. It resides in a dynamic mechanically loaded environment and p......
Stem cell therapy is a promising future enterprise for renal replacement in patients with acute and chronic kidney disea......
Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to in
Telomere shortening and mitochondrial dysfunction are closely linked with the degenerative pathogenesis in humans.Revers......
Neural differentiation from pluripotent stem cells:The role of natural and synthetic extracellular m
Neural cells differentiated from pluripotent stem cells(PSCs), including both embryonic stem cells and induced pluripote......
Beta cell mass and function are decreased to varying degrees in diabetes. Islet cell replacement or regenerative therapy......
Diabetes mellitus(diabetes) is a devastating disease that affects millions of people globally and causes a myriad of com......
诱导型多能干细胞(induced pluripotent stem cells,iPS cells)技术的建立为自体组织工程治疗带来了新的希望。鉴于糖尿病患者常伴......
Pluripotent stem cells(PSCs) are able to differentiate into several cell types, including pancreatic β cells. Different......
Diabetes mellitus, characterized by the impaired metabolism of insulin secretion in b cells, is becoming one of the most......
诱导性多能干细胞(induced pluripotent stem cells,iPSCs)可通过对多种终末分化的体细胞进行外源性重编程而获得。iPSCs作为自体......
Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripo
Multiple sclerosis(MS) is an autoimmune disease of the central nervous system(CNS), with focal T lymphocytic infiltratio......
Pancreatic insulin-secretingβcells are essential in maintaining normal glucose homeostasis accomplished byhighly specia......
Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient durin
Fragile X syndrome(FXS) patients carry the expansion of over 200 CGG repeats at the promoter of fragile X mental retarda......
After the demonstration that somatic cells could be reprogrammed to a pluripotent state,exciting new prospects were open......
AIM: To integrally understand the effects of human vascular endothelial cells(VECs) on the proliferation of vascular smo......
Stem cells have their origins in the embryo and during the process of organogenesis, these differentiate into specialize......
YAP is oppositely regulated in i PSC-induced cardiovascular progenitor cell and vascular smooth musc
AIM: To explore whether YAP protein is important in induced pluripotent stem cell( i PSC)-induced cardiovascular progeni......
On February 11,2020,the World Health Organization officially announced the coronavirus disease 2019(COVID-19)caused by t......
Ethical concerns about stem cell-based research have delayed important advances in many areas of medicine,including card......
Human dental pulp stem cells express many pluripotency regulators and differentiate into neuronal ce
Stem cells were isolated from human dental pulp using an optimized method, in which pulp pieces were digested by enzymes......
Medical research in regenerative medicine and cellbased therapy has brought encouraging perspectives for the use of stem......
Gene therapy is a potentially effective treatment for retinal degenerative diseases.Clustered regularly interspaced shor......
干细胞是一类具有多向分化潜能的细胞群,如胚胎干细胞(embryonic stem cell,ESC)、诱导多潜能干细胞(induced pluripotent stem ce......
感光细胞(Photoreceptors)退化是年龄相关性黄斑变性(Age-related macular degeneration,AMD)和视网膜色素变性(Retinitis pigment......
One of the strategies of treating Parkinson’s disease(PD) is the replacement of lost neurons in the substantia nigra wi......
Previous research has shown that mouse embryonic stem (ES) cells can be induced to form neural cells in adherent monocul......
Developmental potency of mouse primitive ectoderm cells, embryonic ectoderm cells and primordial ger
Developmental potency of primitive and embryonic ectoderm cells from 4.50-day to 6.25-day post-coitum (p.c.)mouse embryo......
Enhancing the efficiency of direct reprogramming of human primary fibroblasts into dopaminergic neur
阜阳市局 £4a 局长——_MINtkMMtgj’#lnH$B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
Diseases and disorders of the central nervous system often require significant interventions to restore lost function du......