polycation相关论文
Self-organized anionic polymer coat enhance the RNA interfere efficiency of polycation vectors in se
Cationized polymer(polycation)is one of the widely used nonviral vectors for siRNA delivery.However,the cytotoxicity is ......
Dead and dying cells release nucleic acids (NA).These extracellular RNAs and DNAs can be taken up by immune cells and ac......
Fabrication of a novel nanoscaled polyplex gene delivery systems based on biodegradable polycation o
A novel nanoscaled gene delivery system was designed to reduce carrier-associated cytotoxicity and to enhance the gene t......
BACKGROUND: It has been reported that chitosan nerve conduits could support axon elongation and improve relevant functio......
目的 制备聚阳离子纳米粒非病毒基因载体:葡聚糖-寡胺化合物。方法 以葡聚糖、过碘酸钠、精胺等为反应物,经多步化学合成制备了该载......
采用静电自组装技术制备了富勒醇与聚对亚苯亚乙烯基(PPV)的前驱体、聚二烯丙基二甲基氯化铵(PDDA)的复合薄膜,利用紫外-可见光吸......
脂质体作为一种重要的非病毒基因载体,在核酸和药物转运方面有着巨大的优势和潜力。近年来脂质体基因载体的研究基础上,主要介绍了......
用L-多聚赖氨酸、聚乙烯亚胺及L-多聚鸟氨酸三种多聚阳离子对壳聚糖进行共混修饰,制备了三种共混材料。在这些材料表面吸附了血清......
目的:优选聚阳离子化合物非病毒基因载体的制备条件,制备优良的基因载体.方法:正交试验法,以生成物的伯胺基含量为考察指标,以反应......
选择2种不同类型的聚阳离子[强电解质型聚二烯丙基二甲基氯化铵(PDDA)和弱电解质型聚盐酸丙烯胺(PAH)],分别和脱氧核糖核酸(DNA)分子通过......