single-cell相关论文
Cells are inherently heterogeneous to achieve a diverse spectrum of biological functions.To understand the underlying pr......
The nanoelectrode-based electrochemical method has been widely used for single-cell analysis because of the advantages o......
RNA sequencing (RNAseq) can reveal gene fusions, splicing variants, mutations/indels in addition to differential gene ex......
The mechanical behavior of individual cells plays an important role in regulating various biological activities at the m......
Colorectal cancer(CRC)progression is associated with cancer cell dedifferentiation and stemness acquisition.Several meth......
Single-cell transcriptome analysis of Oryza sativa mesophyll reveals stochasticity in gene expressio
Single-cell RNA-seq studies in mammalian transcriptome have shown that, even in a seemingly homogenous population, the c......
The ultimate goal of single-cell analyses is to obtain the biomolecular content for each cell in unicellular and multice......
Activation of the heart normally begins in the sinoatrial node(SAN).Electrical impulses spontaneously released by SAN pa......
Background: Single-cell RNA sequencing (scRNA-seq) is an emerging technology that enables high resolution detection ......
The aging of alveolar stem cells has been linked to many chronic lung diseases, including pulmonary fibrosis. However, t......
Single-cell RNA sequencing (scRNA-seq) has enabled high-resolution characterization of molecular sig-natures of tumor-in......
Whole-exome sequencing and microRNA profiling reveal PI3K/AKT pathway’s involvement in juvenile myel
Clinical studies and genetic analyses have revealed that juvenile myelomonocytic leukemia (JMML) is caused by somatic an......
Background: Single-cell RNA-sequencing (scRNA-seq) is a rapidly evolving technology that enables measurement of gene exp......
Deep leaing is making major breakthrough in several areas of bioinformatics.Anticipating that this will occur soon for t......
Global Dynamic Molecular Profiling of Stomatal Lineage Cell Development by Single-Cell RNA Sequencin
The regulation of stomatal lineage cell development has been extensively investigated.However,a comprehensive characteri......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的:通过设计构建基于Linux平台的单细胞转录组病毒信息分析系统,以满足整合多个分析软件,快速分析和利用大规模单细胞转录组测序......
目的 探索鸡EPGCs单细胞克隆建立细胞系的可能性,并对其生物学特性进行鉴定.方法 采取19期和28期的鸡EPGCs,体外培养传至第4代的细......
在系统可编程技术(ISP)是二十世纪九十年代迅速发展起来的一种新技术、它的出现,使得硬件设计逐步软件化,硬件结构的通用性日益增强,本......
RNA-seq and single-cell genomic research emerge as an important research area in the recent years due to its ability to ......
采用^60Co-γ辐射处理马铃薯单细胞,快速高效获得马铃薯突变体材料,为丰富马铃薯育种材料提供支持。以紫色马铃薯‘黑美人’试管苗......
稻瘟病(Magnaporthe grisea)历来是湖北省各稻区危害较严重的病害之一,已造成很大的经济损失。为了解稻瘟病致病性分化,提高湖北省抗病......
18-三体综合征是常见的常染色体非整倍体疾病之一,长期以来人们对18-三体综合征疾病的临床表型(如智力障碍、心脏、肾脏异常等)发......
对蜜蜂早龄胚胎(受精卵)冻融后的DNA质量进行必要的活体筛查与损伤检测,有利于避免将潜在性遗传损害带给后代。本文应用胎盘蓝活体......
【正】Objective:To evaluate retrospectively the effect of general anesthesia on DNA damage in the blood mononuclear cell......
当自然条件下的群体微囊藻转入实验室培养后,它们的胶被多糖往往急剧下降,形态由群体解聚为单细胞。M icrocystis aeruginosaDCA(......
In the present study, the yeast Rhodotorula glutinis has been assessed with the aim of producing microbial lipids from g......
Human T cells are a highly heterogeneous population and can recognize a wide variety of antigens by their T cell recepto......
Hepatocellular carcinoma(HCC)is characterized by high heterogeneity in both intratumoral and interpatient manners.While ......
An efficient in vitro method for rapid vegetative propagation of Bienertia sinuspersici, one of four terrestrial species......
Mesenchymal stem cells(MSCs)are multipotent stromal cells with great potential for clinical applications.However,little ......
Hunting down the dominating subclone of cancer stem cells as a potential new therapeutic target in m
The development of single-cell subclones,which can rapidly switch from dormant to dominant subclones,occur in the natura......
Analysis on a single-cell basis is both fundamental and meaningful in biomedical research and clinical practice.Flow cyt......