soliddispersion相关论文
Self-assembled micelles for enhancing the oral bioavailability of 9-nitrocamptothecin via Soluplus(R
Our study aimed to develop an amorphous 9-nitrocamptothecin solid dispersion(9-NC-SD)using polyvinyl caprolactam-polyvin......
Oral controlled release in accordance with drug adsorption biological rhythm provided by an electros
Polymer has acted as the backbone to support the development of pharmaceutics during the past several decades.The first ......
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EFFECT OF POLYVINYLPYRROLIDIONE(PVP K30)ON SOLUBILITY AND BIOAVAILABILITY OF CURCUMIN IN SOLID DISPE
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OBJECTIVE To prepare the ibuprofen sustained-release dropping pill and evaluate its accumulative release percentage in v......
Preparation and characterization of poorly water-soluble drug glipizide solid dispersions using hot-
The study is aim to prepare and characterize solid dispersions of poorly water-soluble drug glipizide with the intention......
PREPARATION AND EVALUATION OF SOLID DISPERSION FOR IBUPROFEN WITH KOLLICOAT IR AS CARRIER USING A PU
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Purpose: Solid dispersions (SDs) of ibuprofen (IBU) were prepared using a newly developed pulse combustion dryer system-......
[Background] Today formulation development still strongly relies on the traditional trial-and-error approach by individu......
Amorphous solid dispersion(SD)is an effective solubilization technique for water-insoluble drugs....
Investigation molecular dissolution mechanism of ketoprofen ternary solid dispersions by molecular d
[Introduction] Ketoprofen(KET)is a poorly-water soluble drug.To improve the solubility and dissolution rate of ketop......
目的 优化和确定反相高压液相色谱法测定紫杉醇固体分散体中紫杉醇的含量.方法 色谱柱为Phenomenex ODS 3,流动相为甲醇-乙腈-水(4......
奈韦拉平(NVP)是第一代非核苷类逆转录酶抑制药,为治疗艾滋病和预防HIV-1母婴传播的一线药物。其溶解性差,生物利用度低。随着新剂......
Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: Pr
The aim of this work was to develop, optimize and characterize a silymarin-laden polyvinylpyrrolidone (PVP)-polyethylene......
目的:提高难溶药物呋塞米(FD)的溶出度。方法:筛选PVP、玉米淀粉作载体,以磷酸氢二钠-枸橼酸缓冲系统来控制微环境pH值,用溶剂沉降法将FD制成固态分......
目的:建立氨苯砜固体分散体含量测定的高效液相色谱方法.方法:色谱柱为Ultrasphere ODS C18柱(250mm×4.6mm,5μm);流速:1.0mL......