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Design,Synthesis and Biological Evaluation of Thiazolopyrimidin-7-One Derivatives as novel PAM of nA
Alzheimers disease(AD)is a fatal neurodegenerative disease with the deterioration of cognitive and memory functions.Homo......
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通过3-苯基-5-氰基-2-硫代-2，3-二氢-4-乙氧亚甲胺基噻唑（5）与伯胺反应，经中间体甲脒关环，合成了10种新的噻唑并[4，5-d]嘧啶类化合物6a-6......
