thiopurine相关论文
Bone marrow inhibition induced by azathioprine in a patient without mutation in the thiopurine S-met
BACKGROUND Azathioprine(AZA)and its close analog 6-mercaptopurine are thiopurines widely used in the treatment of patien......
硫嘌呤类药物作为一类常用的免疫抑制剂，其疗效和不良反应的差异与转运体的基因多态性的关系已成为研究热点，本文收集并分析了相关转......
目的建立同时测定人红细胞内硫嘌呤药物活性毒性代谢产物6-硫鸟嘌呤核苷酸(6-TGNs)和6-甲基巯基嘌呤(6-MMP)浓度的高效液相色谱法(......
基因多态性是影响巯嘌呤类药物在体内代谢，最终造成药物疗效和毒性差异的主要原因。近年来研究发现，单一药物代谢酶或转运体的基因多......
Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis
AIM: To investigate if azathioprine could reduce adenoma formation in ApcMin/+, a mouse model of sporadic intestinal tum......
Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis
AIM: To investigate if azathioprine could reduce adenoma formation in ApcMin/+, a mouse model of sporadic intestinal tum......
AIM To critically assess the available literature regarding the efficacy of thioguanine treatment in inflammatory bowel ......
AIM To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo.METHO......
AIM To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo.METHO......
Impact of thiopurines and anti-tumour necrosis factortherapy on hospitalisation and long-term surgic
Ulcerative colitis （UC） is a chronic inflammatorycondition affecting the large bowel and is associatedwith a significant r......
