Pd-catalyzed C-C cross-coupling reactions play a vital role in modern organic synthesis.Due to the high cost of Pd as well as environmental and product safety issues,the development of highly active Pd catalytic system is crucial to the industrial applications of these coupling reactions.The ligand structure defines the steric and electronic properties of the palladium catalyst and therefore plays a crucial role in the efficiency of the cross-coupling reaction.The aryl substituted indenyl phosphine ligands developed by our group have been widely used in Suzuki-Miyaura,Sonogashira and Buchwald-Hartwig cross-coupling reactions in water.