Aim: To research the mechanisms of the interaction between the two important channels in repolarization reserve.Methods: According to the transient transfection of different genes, HEK293 cells were d
Objective: To investigate effects of hypertension on the changes in gap junction between vascular smooth muscle cells (VSMCs) in mesenteric resistance artery (MA) of spontaneously hypertensive rats (S
Calcium signaling plays a critical role in regulating various physiological processes.Ca2+ signals can be generated in different pathways, among these, store-operated calcium entry (SOCE), triggered b
Vascular disease increases in incidence with age and is the commonest cause of morbidity and mortality among elderly people.Large-conductance Ca2+-activated K+ (MaxiK) channel, with pore-forming a-sub
A group of exquisitely temperature-sensitive transient receptor potential channels,termed thermoTRPs, serve as cellular temperature sensors.How thermoTRPs can respond to temperature at different level
Glasses and crystals Crystalline SiO2 (quartz) Amorphous SiO2 (glass)Glasses are solids with liquid-like spatial uniformity Amorphous solids for drug delivery, and more Glasses are usually made by coo
OUTLINE · OBJECTIVE-Using model drugs, administered via the inhalation route, determine whether the method of particle engineering impacts the aerodynamic performance · Methods of size reduction · Cha
Outline Ⅰ.The purpose to study Pharmaceutical Cocrystals;Ⅱ.The Improvement of Solubility via Pharmaceutical Cocrystals;Ⅲ.The Improvement of Permeability via Pharmaceutical Cocrystals;Ⅳ.