High Prognostic Value of Minimal Residual Disease Detected by Flow Cytometry-Enhanced Fluorescence i

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Background Acute myeloid leukemia (AML) is generally regarded as a disorder of stem cells,known as leukemic initiating cells (LICs),which initiate the disease and contribute to relapses.Although the phenotype of these cells remains unclear in most patients,they are enriched within the CD34+ CD38- population.In core binding factor (CBF) AML,the cytogenetic abnormalities alsoexist in LIC.
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