Objective: To identify risk factors associated with posttransplant recurrence, and to expand the selection criteria.Methods: Adult patients with HCC who received liver transplantation between November 2004 and September 2012 at our center were recruited in current study (n=241).Clinical and pathological data were retrospectively reviewed.Patients died during the perioperative period or died of non-recurrence causes were excluding from this study (n=25).All potential risk factors were analyzed using uni-and multi-variate analyses.