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  5. Melatonin attenuates arteriosclerosis and endothelial permeability in type 2 diabetic rats by down-r

Melatonin attenuates arteriosclerosis and endothelial permeability in type 2 diabetic rats by down-r

来源 :2014年第十二届全国脂质与脂蛋白学术会议 | 被引量 : 0次 | 上传用户：ceng0606
【摘 要】
：
Melatonin, a pineal hormone, exhibits potential cardiovascular protective properties involving interfering with free radical processes.The development of diabet
【作 者】
：
Song-tao Tang Huan Su Qing Zhou Hua-qing Zhu Yuan Wang 
【机 构】
：
LaboratoryofMolecularBiologyandDepartmentofBiochemistry,AnhuiMedicalUniversity
【出 处】
：
2014年第十二届全国脂质与脂蛋白学术会议
【发表日期】
：
2014年10期
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Melatonin, a pineal hormone, exhibits potential cardiovascular protective properties involving interfering with free radical processes.The development of diabetic macrovascular complication is a multifactorial process.This study was designed to evaluate whether melatonin attenuates arteriosclerosis and endothelial permeability by suppressing myosin light chain kinase(MLCK)/phosphorylation of myosin light chain(p-MLC) system via melatonin receptor(MT1)/ mitogen-activated protein kinase(MAPK) signal transduction.
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