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  5. Use of Alemtuzumab in patients with chronic lymphocytic leukemia with unfavorable prognosis

Use of Alemtuzumab in patients with chronic lymphocytic leukemia with unfavorable prognosis

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：dcqnj
【摘 要】
：
Background.Refractory is one of the critical problems in the course of treatment of chronic lymphocytic leukemia.Presence of cytogenetic abnormalities,such as 11 chromosome deletion (11 q-) and 17 chr
【作 者】
：
T.E.Byalik O.L.Timofeyeva A.A.Chekan A.A.Molodyk N.A.Kupryshyna N.N.Tupitsyn V.B.Larionova T.N.Obukhova E.A.Osmanov 
【机 构】
：
N.N. Blokhin Russian Cancer Research Center,Moscow Russian Federation
【出 处】
：
The 35th World Congress of the International Society of Hema
【发表日期】
：
2014年5期
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Background.Refractory is one of the critical problems in the course of treatment of chronic lymphocytic leukemia.Presence of cytogenetic abnormalities,such as 11 chromosome deletion (11 q-) and 17 chromosome deletion (17 p-) often denote unsatisfactory response to the therapy and a short life expectancy.Alemtuzumab (anti-CD52) is effective in patients with unfavorable prognosis.
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