Single-nucleotide polymorphisms in the hypoxia-inducible factor-1a gene present susceptibility to pa

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户:lifengno1
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Objective: To investigate whether the single-nucleotide polymorphisms of hypoxia-inducible factor 1 alpha (HIF-lα)are involved in the susceptibility of pancreatic ductal adenocarcinoma (PDAC).Methods: S-Genotypes of HIFla were determined in 263patients with pancreatic ductal adenocarcinoma and 271healthy controls.Epidemiological and clinical information were obtained.A multiple unconditional logistic regression model and log-rank tests were used for statistical analysis.
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