Increased glycated albumin and decreased esRAGE levels in serum are related to negative coronary art

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Background This study aimed to evaluate the association of serum levels of glycated albumin (GA) and endogenous secretory receptor for advanced glycation end products (esRAGE) with coronary artery remodeling in patients with type2 diabetes.Methods Serum levels of GA and esRAGE were measured and intravascular ultrasound (IVUS) was performed in 136consecutive diabetic patients with 143 coronary intermediate lesions.The remodeling index (RI) was calculated as the ratio between eternal elastic membrane (EEM) area at lesion site and EEM area at reference segment.Negative remodeling was defined as a RI<1 and positive remodeling as a RI>1.
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