Identify A Rspondin1 and Hormone Signaling Feed Forward Loop Independent of Wntβ-Catenin Signaling

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：xmzh369

【摘要】

：

　　Rspondin 1 (Rspo1) has been underscored as a Wnt agonist, serving as a potent niche factor for stem cells in many tissues.Here we discover a novel role of R

【作者】

：

Cheguo Cai Yi Arial Zeng

【机构】

：

TheStateKeyLaboratoryofCellBiology,InstituteofBiochemistryandCellBiology,ShanghaiInstitutesforBiolog

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

R-spondin1 Areg Hormone Wnt

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　　Rspondin 1 (Rspo1) has been underscored as a Wnt agonist, serving as a potent niche factor for stem cells in many tissues.Here we discover a novel role of Rspo1 in regulating the steroid hormone signaling in the mammary gland through a Wnt-independent pathway.

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Identify A Rspondin1 and Hormone Signaling Feed Forward Loop Independent of Wntβ-Catenin Signaling

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