论文部分内容阅读
Carotenoids are the most important pigments among those occurring in the nature and have been found to afford several beneficial effects including cancer chemoprevention.Fucoxanthin is reported to contribute >10% of the estimated total production of carotenoids.Fucoxanthin has a unique structure including an unusual allenic bond and 5,6-monoepoxide in its molecule.We have found that fucoxanthin showed anti-obesity effect with a new molecular mechanism.Considered as breakthrough discoveries for an ideal therapy of obesity,regulation of UCP expression in adipose tissue (WAT) by food constituent should be studied.Only recently,we showed significant reduction of WAT in wistar rats and obese KK-Ay mice by feeding fucoxanthin.The dairy intake of fucoxanthin to KK-Ay mice also caused a significant reduction of body weight.