Zwitterionic hydrogels enhance angiogenic response,promote complete skin regeneration during full-th

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：whp71518255

【摘要】

：

【作者】

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Zecong Xiao Chaochao He Jingjing Zhu Jingjing Ye Yi Li Anqi Chen Hongxue Shi Hongyu Zhang Xiaokun Li Jian Xiao Jiang Wu

【机构】

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School of Pharmaceutical Sciences,Key Laboratory of Biotechnology and Pharmaceutical Engineering,Wen

【出处】

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Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

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zwitterionic hydrogel wound healing sulfobetaine neovascularization inflammation

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　　Dermal wound healing is a complex process that requires a harmonious interplay working among cells,growth factors,and extracellular matrix (ECM) proteins.This process includes blood clotting,inflammation,new tissue formation and finally tissue remodeling[1].Zwitterionic polymers are found to be more effective for anti-protein adsorption on surface grafting and protein modification.Even more,in vivo implantation has demonstrated that zwitterionic polymers showed much less immune response due to their better nonfouling property[2].

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Zwitterionic hydrogels enhance angiogenic response,promote complete skin regeneration during full-th

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