An atlas of human methylation marks reveals cell-type-specific hypomethylation at super-enhancers

来源 :第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 | 被引量 : 0次 | 上传用户：rinimalebi

【摘要】

：

An atlas of human methylation marks reveals cell-type-specific hypomethylation at super-enhancers.DNA methylation is a key epigenetic mark that is critical for gene regulation in multicellular eukaryo

【作者】

：

Hongbo Liu Qiong Wu Yan Zhang

【机构】

：

Harbin Medical University Harbin Institute of Tec

【出处】

：

第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会

【发表日期】

：

2015年3期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

亚胺培南与头孢哌酮-舒巴坦联合应用对多粘菌素中介的多重耐药肺炎克雷伯菌的协同作用

目的：评价多种抗生素及其联合应用对产碳青霉烯酶肺炎克雷伯菌的体外抗菌活性,寻找有效的联合用药策略。方法：选取24 株临床分离的多重耐药肺炎克雷伯菌株,经改良Hodge 实验验证受试菌株是否产碳青霉烯酶；采用微量肉汤稀释法,测定多粘菌素(CST)对各菌株的最低抑菌浓度(Minimum Inhibitory Concentration,MIC),筛选出7 株MIC 中介的肺炎克雷伯菌,并测量亚胺培南(

会议

肺炎克雷伯菌碳青霉烯酶协同作用

Reprogramming induced intermediate cells to iPSCs by small molecule compounds

The induction of pluripotent stem cells(iPSCs)by transcriptional factors is an important way to generate cells for therapeutic applications.However,the mechanism of reprogramming is poorly understood.

会议

Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent c

Nucleosome positioning and histone modification play a critical role in gene regulation,but their role during reprogramming has not been fully elucidated.Here,we determined the genome-wide nucleosome

会议

nail1-Dependent p53 Repression Regulates Expansion and Activity of Tumour-Initiating Cells in Breast

The zinc-finger transcription factor,Snail1,is inappropriately expressed in breast cancer and associated with poor prognosis.While interrogating human databases,we discovered unexpectedly a marked dec

会议

Differentiation of Adipose Derived Mesenchymal Stem Cells into Corneal Epithelium-like Cells Driven

By means of immunofluorescence and western blotting,it was found that pax6 gene transfection could induce differentiation of ADMSCs into corneal epithelial-like cells.

会议

Tissue regeneration,stem cells,and transplantation

会议

Road to the Clinic:Development of Stem Cell Therapeutics Using ES Cells/iPS Cells and Functional Gen

会议

A preliminary in vivo study of the effects of OPN in rat liver regeneration induced by partial hepat

Purpose: Osteopontin(OPN),as a member of Th1 cytokine secreted by activated lymphocytes and macrophages,could promote inflammation response,cell proliferation or migration and then participate in the

会议

osteopontinshRNAtail intravenous injectionpartial hepatectomyrat liver regen

Generation of 3D retinal tissues from urine-derived hiPSCs for treatment of retinal diseases

Background and purpose: Retinal degenerative diseases are the major causes of vision loss without effective treatment so far.Human induced pluripotent stem cells(hiPSC)hold great promise for treating

会议

Mitochondrial Remodeling in Somatic Cell Reprogramming

会议

An atlas of human methylation marks reveals cell-type-specific hypomethylation at super-enhancers

与本文相关的学术论文