osteopontin相关论文
目的:探讨血清骨桥蛋白、骨保护素与2型糖尿病(type 2 diabetes mellitus,T2DM)合并冠心病的关系,并评价T2DM患者血清骨桥蛋白、骨保护......
Osteopontin expression is associated with hepatopathologic changes in Schistosoma japonicum infected
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MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human cho
The aim of this study was to determine the specific microRNA (miRNA) that regulates expression of osteopontin (OPN) in o......
Objective The purpose of this study is to clarify the deference of OPN expression in ligamentum flavum cells(LFC)between......
OPN is known to be a key regulator in a variety of cellular events, which potentially leads to increased angiogenesis an......
The clinical significance of serum and joint fluid osteopontin levels in juvenile idiopathic arthrit
Objective:To evaluate the clinical significance of osteopontin(OPN)in serum and joint fluid in juvenile idiopathic arthr......
目的: Bioinformatics analysis combined with metastasis-related genes microarray array showed that osteopontin could be im......
Decreased osteopontin expression as a reliable prognostic indicator of improvement in pulmonary tube
Background and Objective: Osteopontin (OPN) expression is increased during the course of various chronic inflammatory di......
Background: Osteopontin is increased in bacterial lung infection.However, the level of osteopontin in virus-induced lung......
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Runx2 mediated misregulation of Osteopontin splicing promoted Epithelial-Mesenchymal Transition in n
Background: Osteopontin(OPN)is a phosphorylated glycoprotein frequently overexpressed in cancers,including lung cancer i......
The clinical significance of serum and joint fluid osteopontin levels in juvenile idiopathic arthrit
Objective : To evaluate the clinical significance of osteopontin (OPN) in serum and joint fluid in juvenile idiopathic a......
Objective To explore the key regulatory genes associated with lung cancer in order to reduce its occurrence and progress......
Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes cancer metast
Objective Hepatocellular carcinoma(HCC)is the most frequent primary liver cancer and is the third leading cause of cance......
ObjectiveToinvestigateeffectofnicotinicacidonexpressionofosteopontininrabbitofkneeosteoarthritisbydetecttheexpressionofO......
A preliminary in vivo study of the effects of OPN in rat liver regeneration induced by partial hepat
Purpose: Osteopontin(OPN),as a member of Th1 cytokine secreted by activated lymphocytes and macrophages,could promote in......
Aim: Osteopontin (OPN), an extracellular matrix protein, has a functional RGD domain for binding to integrin and has bee......
Osteopontin mediates hyperbaric oxygen preconditioning induced neuroprotection against ischemic stro
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Background and aims:Vascular calcification is common in people with diabetes and its presence predicts premature mortali......
Arterial calcification occurs with increasing age and accelerates in patient with diabetes.Its presence predicts prematu......
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Effect of human osteopontin on proliferation, transmigration and expression of MMP-2 and MMP-9 in os
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AIM:to analyze adipokine concentrations,insulin resistance and hepatic expression of suppressor of cytokine signaling 3(......
目的探讨甲氨喋呤对胶原诱导性关节炎(collagen-induced arthritis,CIA)大鼠滑膜骨桥蛋白(osteopontin,OPN)及其受体整合素αvβ3表达的......
目的探讨原发性肾病综合征的诊断标志物和中药肾康灵药物治疗靶点。方法将50只SD大鼠随机分为正常组、模型组、泼尼松组、中西药组......
泽泻醇提物长期喂养大鼠,探究其对大鼠的肾毒性作用,并研究其肾毒性的可能的分子机制。60只雌性大鼠随机分为空白组,雷公藤对照组,......
Background Osteopontin(OPN)is one kind of cytokine which can play a number of roles in promoting activation of Tlymphoc......
风湿免疫性疾病是一类累及多系统、多器官,临床表现复杂、病程迁延反复的自身免疫性疾病.其病因、发病机制尚未完全明了,一般认为......
Implication of Expression of Osteopontin and Its Receptor Integrin αvβ3 in the Placenta in the Devel
To investigate the expression of osteopontin (OPN) and its receptor integrin αvβ3 in the placental tissue from pregnan......
Effects of Perindopril on Left Ventricular Remodeling and Osteopontin Expression in Rats With Myocar
Objectives To observe the effects of perindopril on left ventricular remodeling and myocardial osteopontin expression in......
目的:拟以C57糖尿病小鼠为研究对象,建立糖尿病小鼠OPN-/-MSCs组、糖尿病小鼠MSCs组及溶剂组对照组,采用小鼠创面愈合率检测、HE染......
目的观察骨桥蛋白(osteopontin,OPN)在退行性变升主动脉瘤(Degenerative ATAA,DATAA)中的表达,初步探讨OPN及平滑肌细胞表型转化在......
Effects of OPN-002-si RNA transfection on intimal hyperplasia and OPN,TGF-β1,PCNA expression after c
Objective To investigate the effects of OPN-002-si RNA transfection on intimal hyperplasia and osteopontin(OPN),transfor......
科学家们通过对肿瘤细胞进行的基因分析,可以预测肝癌的常见类型——肝细胞癌是否由原发部位向外扩散。美国国立癌症研究所(NCI)......
Enhancement of osteopontin expression in HepG2 cells by epidermal growth factor via phosphatidylinos
AIM:Osteopontin (OPN) is a phosphorylated glycoproteinwith diverse functions including cancer development,progression a......
Hyaluronic acid induces osteopontin via the phosphatidylinositol 3-kinase/Akt pathway to enhance the
Hyaluronic acid (HA) binds to cell-surface receptors such as CD44, and seems to be involved in cell adhesion, motility, ......
成骨细胞由具有多向分化潜能的间充质细胞经骨原细胞、前成骨细胞分化而来,它一旦终末分化以后就分泌产生各种细胞外基质蛋白,如I......
目的:骨桥蛋白(Osteopontin,OPN)是一种分泌型磷酸化糖蛋白,具有细胞黏附蛋白和细胞因子的双重作用,能够与破骨细胞表面αvβ3......
Matricellular proteins as possible biomarkers for early brain injury after aneurysmal subarachnoid h
Aneurysmal subarachnoid hemorrhage remains devastating,and the most important determinant of poor outcome is early brain......
近年来,在世界范围内乳腺癌的发病率呈逐年升高的趋势,骨桥蛋白(osteopontin,OPN)是一种分泌型、黏附性的糖基化磷蛋白.近年来的研......
目的 探讨类风湿关节炎患者血清人软骨糖蛋白39(HC gP39)、骨桥蛋白(OPN)及类风湿因子(RF)水平变化及其临床意义.方法 采用ELISA法......
目的:研究骨桥蛋白(OPN)和磷脂酰肌醇3-激酶(PI3K)蛋白在在宫颈癌癌变过程中的表达及其与临床病理特征的关系,并分析宫颈癌组织中......
目的探讨骨桥蛋白(OPN)和Stathmin-1表达在前列腺癌复发和生存预后评估中的应用。方法选取2014年6月至2016年6月治疗的前列腺癌患者1......
眼部新生血管是眼部疾病中致盲的主要原因之一.常见的致盲眼病,如糖尿病视网膜病变、年龄相关性黄斑变性、感染性角膜炎等均与新生......