【摘 要】
：
目的 探讨无精子患者血清抑制素B与睾丸抽吸(TESE)成功率的关系.方法 血清抑制素B采用双抗夹心酶联免疫吸附技术,血清FSH采用化学发光法检测.结果 回顾性分析了91例无精子症患者的FSH及血清抑制素B水平,其中42例非梗阻性无精子症患者血清抑制素B水平(53.18 ±27.26)明显低于45例正常对照组(129.58±56.6),差异有显著性(P＜0.05),血清FSH水平(19.18±13.
【机 构】
：
锦江区妇幼保健院生殖中心 四川大学华西医院
【出 处】
：
中华医学会第七次全国生殖医学学术会议
论文部分内容阅读
目的 探讨无精子患者血清抑制素B与睾丸抽吸(TESE)成功率的关系.方法 血清抑制素B采用双抗夹心酶联免疫吸附技术,血清FSH采用化学发光法检测.结果 回顾性分析了91例无精子症患者的FSH及血清抑制素B水平,其中42例非梗阻性无精子症患者血清抑制素B水平(53.18 ±27.26)明显低于45例正常对照组(129.58±56.6),差异有显著性(P＜0.05),血清FSH水平(19.18±13.28)明显高于正常对照组(4.28±1.65),差异有显著性(P＜0.01);其中有9例患者成功找到精子.49例梗阻性无精子患者与对照组血清抑制素B、FSH水平均无显著差异.结论 血清抑制素B与FSH一样可以评价男性精子发生以及睾丸的功能,可作为睾丸精子抽吸能否成功的重要参考,但其检测水平与FSH一样,受多种与精子无关因素的影响,测定的正常参考值波动范围较大,对临床诊断能否获取精子的结局有预测作用,如果能够结合患者病史、体任、染色体及睾丸活检等结果来综合判断更好.
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