【摘 要】
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Background: Numerousreports have indicated dys-regulated expansion of cytokineprofiles from specific T-cell subsets in immune thrombocytopaenia (ITP) Inparticular, elevated interleukin-6 (IL-6) levels
【机 构】
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Peking University People's Hospital, Peking University Institute of Hematology 100044
【出 处】
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中华医学会第15次全国血栓与止血学术会议
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Background: Numerousreports have indicated dys-regulated expansion of cytokineprofiles from specific T-cell subsets in immune thrombocytopaenia (ITP) Inparticular, elevated interleukin-6 (IL-6) levels inversely correlate withplatelet count.β2-glycoprotein I (β2-GPI) is a plasma glycoprotein that actsas a complement regulator (Gropp et al.Blood.2011) and might be involved inthe pathogenesis of ITP.Recent studies have proven the presence of β2-GPI mRNAin human peripheral blood monocytes.
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