Mir-16a/adrb2通过MAPK/Erk调节肝癌复发转移的机制研究

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户：michael8363

【摘要】

：

目的肝癌复发转移是当前肝癌治疗的重大难题,G蛋白偶联受体超家族(GPCR)是肝癌治疗的研究热点,与肿瘤的发生发展、代谢性疾病等重大疾病的主要机制息息相关。肾上腺素受体(ADR)是一种重要的GPCR 蛋白,ADR 信号通路在肿瘤复发转移中发挥着关键作用,研究表明β 2 肾上腺素受体(ADRB2)是肝癌细胞表面最重要的ADR,本研究拟聚焦于ADRB2 信号受体通路,阐明ADR2信号通路(β 2-AR

【作者】

：

张轩煜徐骁

【机构】

：

浙江大学医学院附属第一医院

【出处】

：

2019中国肿瘤学大会

【发表日期】

：

2019年7期

【关键词】

：

肝癌 β2受体复发转移

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Mir-16a/adrb2通过MAPK/Erk调节肝癌复发转移的机制研究

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