【摘 要】
：
Objective To investigate the value of model for end-stage liver disease (MELD) score, MELD with incorporation of serum sodium (MELD-Na) score and integrated MELD (iMELD) score for evaluation of progno
【机 构】
：
Tianjin Second Peoples Hospital
【出 处】
：
中华医学会第十六次全国病毒性肝炎及肝病学术会议
论文部分内容阅读
Objective To investigate the value of model for end-stage liver disease (MELD) score, MELD with incorporation of serum sodium (MELD-Na) score and integrated MELD (iMELD) score for evaluation of prognosis of chronic liver failure.Methods A total of 159 consecutive patients with chronic liver failure were included in the study and divided into two groups (death group and survival group) according to the prognosis.The levels of total bilirubin (TBIL), serum creatinine (Cr), prothrombin time (PT), PT international normalized ratio (INR), Serum sodium (Na), age, MELD, MELD-Na and iMELD were calculated respectively and the comparative analysis was performed.Areas under the receiver operating characteristic curve (AUC-ROC) of MELD, MELD-Na and iMELD were used to assess the prognosis in patients with chronic liver failure.
其他文献
Background Depression, a common side effect of interferon therapy in patients with chronic hepatitis C, is closely associated with antiviral dosage reduction, discontinuation and failure of treatment.
Aim uncover the possible immune response to HBV naked core particle in hydrodynamic injection mice model.Methods Plasmids expressing wild type of HBV core protein (HBcWT), or HBcK96R mutation which ab
Hepatitis B virus (HBV) polymerase (pol) gene has been demonstrated to play an important role in the progression of liver disease and in fulminant hepatitis.Previous studies from our laboratory have s
原发性肝癌恶性程度高,起病隐匿,病情进展快,容易复发转移;而且我国肝癌多发生在肝炎、肝硬化基础之上,不仅造成机体的损伤,还降低肝脏的储备功能,严重影响肿瘤的治疗和预后.肝癌的治疗不仅需关注消除肿瘤本身,而且必须同时注重保护患者肝功能、减少肝功能损害.肝癌规范治疗的最主要评价标准是患者生存获益.
Background Clinical use of bioartificial liver (BAL) strongly relies on the development of human liver cell lines.The aim of this study was to establish and assess the potential usage of the HepG2 cel
Background & Aims The woodchuck model is an informative model for studies on hepadnaviral infection.In this study, woodchuck hepatitis virus (WHV) transgenic (Tg) mouse models based on C57BL/6 mice we
We have previously shown that polyinosinic-polycytidylic acid (poly (I ∶ C)) activates murine hepatic cells to produce interferon (IFN) and suppresses HBV replication in vitro.Therefore, we addressed
Background and ains Microvesicles (MVs) are membrane vesicles that are released from multiple cells.MVs contain proteins, lipids and nucleic acids of the original cells.The microRNAs (miRNAs) released
Objective To evaluate the effect of Fuzheng Huayu (FZHY) capsule on epithelial to mesenchymal transition (EMT) of hepatic stellate cells (HSCs) and EMT-based liver fibrosis.Methods Primary rat HSCs we
Objective Peroxisome proliferator-activated receptor gama (PPARgama) possesses general beneficial effects on non-alcoholic fatty liver disease, such as attenuating steatosis, inflammation and fibrogen