GAS2维持慢性粒细胞白血病细胞生长的功能研究

来源 :中国细胞生物学学会2013年全国学术大会 | 被引量 : 0次 | 上传用户：freegfly

【摘要】

：

慢性粒细胞白血病(CML)是正常造血干细胞获得性形成BCR-ABL融合基因而诱发的克隆性血液肿瘤.抑制BCR-ABL酪氨酸激酶的小分子化合物,如Imatinib mesylate能使慢性期患者得到有效缓解,但单一药物尚不能治愈该疾病;这表明深入研究CML致病分子机制、寻找新的治疗靶标仍是CML研究的重点.

【作者】

：

葛跃马文娟吴洁张秀艳周海侠刘红吴德沛赵昀

【机构】

：

苏州大学唐仲英血液学研究中心,苏州215123 苏州大学附属第一人民医院,苏州215006

【出处】

：

中国细胞生物学学会2013年全国学术大会

【发表日期】

：

2013年12期

【关键词】

：

CML calpain beta-catenin GAS2 HNRPDL

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GAS2维持慢性粒细胞白血病细胞生长的功能研究

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