【摘 要】
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Type 1 diabetes is also called insulin-dependent diabetes or autoimmune diabetes means that the body destroys its own insulin-producing cells.In particular, the pancreas produces insufficient insulin
【机 构】
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Graduate Institute of Biotechnology, Chinese Culture University, 55 HwaKang Rd.YangMingShan, Taipei
【出 处】
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世界中医药学会联合会中药鉴定专业委员会成立大会暨第一届学术年会
论文部分内容阅读
Type 1 diabetes is also called insulin-dependent diabetes or autoimmune diabetes means that the body destroys its own insulin-producing cells.In particular, the pancreas produces insufficient insulin (insulin deficiency absolute or relative to the needs of the body) or because cells do not use insulin, increases blood glucose and urine glucose.Type 1 diabetes tends to occur in young, usually under 30 years of age.Diabetes is a risk factor to increase the occurrence and severity of cardiovascular events.According to statistics, cardiovascular complications are the leading cause of death of 3/4 of the number of diabetic patients over 40 years old.Sesame (Sesamumindicum) is one of nature medicine has been know with many function for good health.Sesamin-a lignan extracted from the sesame seed -have many beneficial effects such as hypoglycemia, ameliorate lipid metabolism, antioxidant and hypolipidemic activity, reduced cholesterol, and exhibited anti-inflammatory activity.Oral administration of sesamin extract for four weeks (100 mg / kg BW and 200 mg / kg BW) was slightly improved blood glucose levels and body weight in rats with type 1 diabetes.But it was significantly ameliorated heart rate, blood pressure and QT interval in male diabetes rats.This indicated that sesamin has a positive effect in reducing cardiovascular complications in diabetic subj ects.
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