论文部分内容阅读
目的分析肝硬化合并上消化道出血应用凝血酶与奥曲肽联合治疗的临床效果。方法肝硬化合并上消化道出血患者52例,随机分为对照组25例和观察组27例。对照组单纯应用奥曲肽治疗,观察组应用凝血酶与奥曲肽联合治疗,比较两组止血时间、症状好转时间与临床疗效。结果观察组止血时间(17.0±2.1)h与症状好转时间(23.5±3.2)h显著少于对照组的(28.9±4.1)、(72.8±6.5)h,总有效率(96.30%)高于对照组(76.00%),差异均具有统计学意义(P<0.05)。结论肝硬化合并上消化道出血应用凝血酶与奥曲肽联合治疗止血迅速,效果显著,切实可行,值得推广。
Objective To analyze the clinical effect of combination therapy of thrombin and octreotide on cirrhosis with upper gastrointestinal hemorrhage. Methods 52 patients with cirrhosis and upper gastrointestinal bleeding were randomly divided into control group (n = 25) and observation group (n = 27). The control group was treated with octreotide alone. The observation group was treated with thrombin and octreotide. The bleeding time, symptom improvement time and clinical effect were compared between the two groups. Results The bleeding time (17.0 ± 2.1) h and symptom improvement time (23.5 ± 3.2) h in observation group were significantly lower than those in control group (28.9 ± 4.1) and (72.8 ± 6.5) h, and the total effective rate was 96.30% Group (76.00%), the difference was statistically significant (P <0.05). Conclusions The combination of thrombin and octreotide in the treatment of cirrhosis combined with upper gastrointestinal hemorrhage has the advantage of rapid hemostasis, remarkable effect, practicality and worthy of popularization.