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目的探讨劳拉西泮治疗老年急性心肌梗死伴焦虑症患者的临床疗效。方法选取2013年6月至2014年7月河北省廊坊市长征医院收治的106例急性心肌梗死伴焦虑症患者作为研究对象,按随机数字表法将其分为对照组(56例)和观察组(50例)。对照组患者给予常规治疗联合心理干预,观察组患者在对照组基础上采用劳拉西泮进行治疗,比较两组患者的症状改善情况、硝酸甘油用量、临床疗效、汉密顿焦虑量表(HAMA)评分及不良反应发生情况。结果观察组患者的心绞痛次数、硝酸甘油用量均明显少于对照组,病情持续时间明显短于对照组,差异均有统计学意义(均P<0.05);观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的HAMA评分明显低于对照组,差异有统计学意义(P<0.05)。结论急性心肌梗死合并焦虑症患者采用常规治疗加劳拉西泮治疗,可有效改善患者焦虑症状,减少心绞痛发作次数,临床应用效果明显。
Objective To investigate the clinical efficacy of lorazepam in the treatment of elderly patients with acute myocardial infarction and anxiety. Methods From June 2013 to July 2014, 106 patients with acute myocardial infarction and anxiety admitted to Changzheng Hospital of Langfang City, Hebei Province were selected as the research objects. According to the random number table, they were divided into control group (56 cases) and observation group (50 cases). Patients in the control group were treated with conventional therapy combined with psychological intervention. Patients in the observation group were treated with lorazepam on the basis of the control group. The improvement of symptoms, the amount of nitroglycerin, the clinical efficacy, HAMA ) Score and adverse reactions occurred. Results The number of angina pectoris and nitroglycerin in the observation group were significantly less than those in the control group, and the duration of the disease was significantly shorter than that in the control group (all P <0.05). The total effective rate of observation group was significantly higher In the control group, the difference was statistically significant (P <0.05). After treatment, the HAMA score of the observation group was significantly lower than that of the control group (P <0.05). Conclusion Acute myocardial infarction with anxiety patients treated with conventional therapy plus lorazepam can effectively improve the symptoms of patients with anxiety and reduce the number of angina attacks, the clinical application of significant results.