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目的观察加味八珍汤对艾滋病抗反转录病毒治疗(ART)诱发高乳酸血症的作用。方法 70例艾滋病ART后出现高乳酸血症患者,采用抽签法随机分为两组,治疗组35例给予ART联合加味八珍汤,对照组35例给予ART并口服碳酸氢钠片,疗程为48个月。每6个月检测血乳酸1次,比较两组患者血乳酸值的变化。结果治疗乏力、四肢麻木、肌肉疼痛、趾痛临床症状评分明显少于对照组(P<0.05)。治疗组血乳酸值小于对照组(P<0.05)。结论加味八珍汤可在一定程度上缓解ART诱发的高乳酸血症。
Objective To observe the effect of Jiawei Bazhen Decoction on AIDS induced anti-retroviral therapy (ART) induced hyperlipidemia. Methods 70 cases of AIDS patients with hyperlactatemia after ART were randomized into two groups by random sampling. 35 cases in the treatment group were treated with ART combined with Modified Bazhen Decoction, 35 cases in the control group were given ART and sodium bicarbonate tablets for 48 months Months. Blood lactate was tested every 6 months and the changes of blood lactate level were compared between the two groups. Results The scores of clinical symptoms of weakness, numbness of limbs, muscle pain and toe pain were significantly less than those of the control group (P <0.05). The blood lactate level in the treatment group was less than that in the control group (P <0.05). Conclusion Modified Bazhen Decoction can relieve ART-induced hyperlipidemia to a certain extent.