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目的:了解我县在大力推广乙肝疫苗注射后3~6岁儿童乙肝病毒(HBV)感染情况。方法:于2009年3~6月对我县3~6岁入园儿童2607名,采用酶联免疫吸附试验(ELISA)检测血清中HBsAg、HBsAb、HBeAg、HBeAb、HBcAb。结果:总HBsAg阳性率为0.84%,总HBsAb阳性率为62.18%,HBsAb阴性率为36.98%,与经济欠发达城市相比,我县在降低儿童HBV感染率与提高其保护率方面效果令人满意。该批儿童感染模式共有7种。HBsAg、HBsAb阳性率,HB-sAb阴性率性别的差异无显著性。结论:乙肝疫苗是目前预防乙肝病毒感染的有力手段。如何最大可能地提高儿童乙肝疫苗接种率,提高免疫接种的HBsAg阳性率,加强乙型肝炎防治知识宣传,从而有效地控制和减少儿童HBV的传播,是广大医务工作者的一项重要任务。
Objective: To understand the county in promoting hepatitis B vaccine 3 to 6 years old children after hepatitis B virus (HBV) infection. Methods: From March to June 2009, 2607 children admitted to our county were enrolled in this study. Serum HBsAg, HBsAb, HBeAg, HBeAb and HBcAb were detected by enzyme-linked immunosorbent assay (ELISA). Results: The positive rate of total HBsAg was 0.84%, the positive rate of total HBsAb was 62.18%, and the negative rate of HBsAb was 36.98%. Compared with the economically less developed cities, our county had a significant effect in reducing the HBV infection rate and increasing the protection rate of children satisfaction. The batch of children infected with a total of seven kinds. HBsAg, HBsAb positive rate, HB-sAb negative rate sex difference was not significant. Conclusion: Hepatitis B vaccine is a powerful means to prevent hepatitis B virus infection. How to increase the rate of hepatitis B vaccination in children to the greatest extent possible, increase the HBsAg positive rate of immunization and enhance the publicity of hepatitis B prevention and control information so as to effectively control and reduce the spread of HBV in children is an important task for medical workers.