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目的随着早产儿抢救技术的不断提高,存活者逐渐增多。但这类患儿面临感染、喂养困难、营养、黄疸等问题,并且由于疾病的非特异性,临床上有时候很难及时的发现,因此成为早产儿中的管理重点,为更好管理这些早产儿,我院近年采取了血清前白蛋白测定来进行监测,取得了一定的效果,特总结分析以期能对临床工作有所帮助。方法对我院2007年05月至2008年4月间,出生<72h的262例住院早产儿,分成普通早产儿组、静脉营养早产儿组和感染早产儿组分别进行血清前白蛋白测定。结果三组早产儿血清前白蛋白测定中,生后7d和14d以感染组血清前白蛋白含量最低,静脉营养组血清前白蛋白含量最高;随着感染的控制,感染组血清前白蛋白含量明显增高。结论血清前白蛋白,结合C-反应蛋白(CRP),能早期发现早产儿的感染,并判断感染控制情况;同时对早产儿静脉营养的有效性进行判断,可以为临床中的一个重要指标。
Objective With the continuous improvement of rescue techniques for premature infants, survivors gradually increased. However, these children are faced with the problems of infection, feeding difficulties, nutrition, jaundice and the like, and because of the nonspecific nature of the disease, it is sometimes difficult to find clinically in time. Therefore, it is a management priority in premature infants. To better manage these premature infants , Our hospital in recent years to take pre-serum albumin measurement to monitor and achieved some results, especially summary analysis in order to be helpful for clinical work. Methods A total of 262 inpatients with preterm infants who were born within 72 hours from May 2007 to April 2008 in our hospital were divided into normal premature infants, preterm infants with intravenous nutrition and preterm infants infected with preeclampsia respectively. Results Serum prealbumin in preterm infants in the three groups had the lowest levels of prealbumin in the infected group at 7d and 14d after birth and the highest level of prealbumin in the intravenous nutrition group. With the control of infection, the serum prealbumin level Significantly higher. Conclusions Pre-serum albumin and C-reactive protein (CRP) can detect the infection of premature infants early and judge the infection control. At the same time, judging the effectiveness of intravenous nutrition in premature infants can be an important clinical indicator.