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目的观察盐酸曲唑酮合并心理健康教育治疗冠心病心绞痛疗效。方法48例患者随机分为对照组和干预组,对照组常规予休息、吸氧、硝酸酯制剂、钙通道阻滞剂、丹参、小剂量阿司匹林、对症等治疗。心绞痛发作均舌下含服硝酸甘油,0.3~0.6 mg/次。干预组患者在常规治疗基础上加用盐酸曲唑酮,50 mg,3次/d,口服,另加心理健康教育,治疗前后观察心绞痛发作频率、程度、持续时间,心电图、心肌酶谱变化及HAMA评分的变化。结果干预组无论在心绞痛症状还是HAMA评分的改善均明显优于对照组。结论盐酸曲唑酮合并心理健康教育治疗冠心病心绞痛,能明显改善患者焦虑症状,提高临床疗效。
Objective To observe the curative effect of trazodone hydrochloride combined with mental health education on angina pectoris of coronary heart disease. Methods Forty-eight patients were randomly divided into control group and intervention group. The control group was treated with routine resuscitation, oxygen inhalation, nitrates preparation, calcium channel blockers, salvia miltiorrhiza, low dose aspirin and symptomatic treatment. Angina attacks are sublingual nitroglycerin, 0.3 ~ 0.6 mg / time. The patients in the intervention group were given trazodone 50 mg three times a day on the basis of routine treatment, with the addition of mental health education. The changes of angina pectoris frequency, degree, duration, electrocardiogram (ECG) and myocardial enzymes were observed before and after treatment. HAMA score changes. Results The intervention group was better than the control group both in the improvement of angina pectoris symptom and HAMA score. Conclusion Trazodone hydrochloride combined with mental health education in the treatment of coronary heart disease angina pectoris can significantly improve the symptoms of patients with anxiety and improve clinical efficacy.