论文部分内容阅读
目的:探讨以奈达铂为主的化疗应用于妇科肿瘤治疗中的近期疗效和不良反应情况。方法:选取2013年9月至2016年9月收治的妇科肿瘤患者28例,随机分为两组,各14例。对照组行奥沙利铂化疗,观察组行奈达铂为主的化疗,观察并记录两组近期疗效和不良反应发生率,展开比较分析。结果:观察组近期治疗有效率略高于对照组,但差异不显著(P>0.05);观察组白细胞下降、发热、中性粒细胞下降和神经感觉异常发生率低于对照组,差异显著(P<0.05);观察组恶心呕吐、皮疹发生率与对照组相比,无显著差异(P>0.05)。结论:以奈达铂为主的化疗应用于妇科肿瘤治疗中疗效确切,可减少不良反应,值得推广。
Objective: To investigate the short-term curative effect and side effects of nedaplatin-based chemotherapy in the treatment of gynecologic oncology. Methods: Twenty-eight patients with gynecologic cancer who were admitted to our hospital from September 2013 to September 2016 were randomly divided into two groups (n = 14 in each group). The control group received oxaliplatin chemotherapy, and the observation group was treated with nedaplatin-based chemotherapy. The short-term curative effect and incidence of adverse reactions were observed and recorded. Results: The treatment efficiency in the observation group was slightly higher than that in the control group (P> 0.05). The incidences of leukopenia, fever, neutrophil decline and neurosensory abnormalities in the observation group were lower than those in the control group P <0.05). There was no significant difference in the incidence of nausea, vomiting and rash between the observation group and the control group (P> 0.05). Conclusion: Nedaplatin-based chemotherapy is effective in gynecologic oncology and can reduce side effects and is worth promoting.