一、定义糖尿病足病变是指以全身各种大小血管损害与各种神经损害为基础 ,引起的下肢感染、溃疡、组织破坏。严重者须截肢 ,故应积极治疗。二、病理生理与预防的原则1.发病率　在日本的发病率在明显增多 ,认为与下肢缺血性病变的增加有关 ,据世界统计可出现于 15 %的糖尿病患者 First, the definition of diabetic foot lesions refers to the body of various sizes of vascular damage and various nerve damage, based on the lower extremity infection, ulcers, tissue damage. In severe cases amputation, it should be actively treated. Second, the principles of pathophysiology and prevention 1. The incidence of morbidity in Japan increased significantly, that is associated with lower extremity ischemic lesions increased, according to world statistics can occur in 15% of diabetic patients