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目的研究玻璃体切割手术对糖尿病玻璃体视网膜病变患者角膜内皮的影响。方法以郑州艾格眼科医院2013年2月至2014年12月择期行玻璃体切割手术的100例玻璃体视网膜病变患者为研究对象,其中非糖尿病玻璃体视网膜病变60例为对照组,糖尿病玻璃体视网膜病变40例为观察组,手术前后定期行角膜内皮镜检查,比较两组手术前后角膜内皮细胞面积变异系数(CV)、平均细胞面积标准差(SD)、角膜内皮细胞密度(CD)、六角形细胞百分比值(RHC)指标。结果两组手术前后不同时间点CD、SD、CV比较差异均未见统计学意义(P>0.05)。观察组术后1周、术中1个月、术后3个月RHC明显低于对照组,差异有统计学意义(P<0.01)。结论糖尿病玻璃体视网膜病变患者玻璃体切割手术前后角膜内皮细胞变化以细胞形态为主,呈可逆性改变特点。
Objective To study the effect of vitrectomy on corneal endothelium in patients with diabetic vitreoretinopathy. Methods One hundred patients with vitreoretinopathy underwent vitrectomy from February 2013 to December 2014 in Zhengzhou Iger Eye Hospital were enrolled. Among them, 60 cases of non-diabetic vitreoretinopathy as control group, 40 cases of diabetic vitreoretinopathy The observation group received routine corneal endoscopy before and after operation. The CV, CV, CD, and hexagonal percentage of corneal endothelial cells before and after surgery were compared RHC) indicator. Results There was no significant difference in CD, SD and CV between two groups before and after operation (P> 0.05). The observation group 1 week after surgery, intraoperative 1 month, 3 months postoperative RHC was significantly lower than the control group, the difference was statistically significant (P <0.01). Conclusion The changes of corneal endothelial cells before and after vitreoretinal surgery in patients with diabetic vitreoretinopathy are characterized by cell morphology and reversible changes.