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目的探讨国产与进口卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床疗效。方法收集2014年1—12月收治的300例产妇资料,将产妇依据治疗方式不同分为两组,各150例。对照组产妇给予进口卡前列素氨丁三醇注射液,观察组产妇给予国产卡前列素氨丁三醇注射液。比较两组患者的治疗效果。结果两组产妇剖宫产术中出血量、术后2 h出血量及总出血量、产后24 h Hb下降值和RBC下降、临床总有效率比较,差异均无统计学意义(均P>0.05);观察组产妇的治疗平均费用低于对照组,腹泻、头痛、恶心呕吐发生率均明显高于对照组,差异均有统计学意义(均P<0.05)。结论深部肌内注射国产卡前列素氨丁三醇注射液可降低产妇产后出血量,增加子宫收缩力,效果明显,安全性高,价格实惠,产妇更容易接受。
Objective To investigate the clinical efficacy of domestic and imported card prostaglandin trometamol injection in treating postpartum hemorrhage with uterine atony. Methods The data of 300 maternal women who were admitted from January to December 2014 were collected. The maternal women were divided into two groups (150 cases) according to the different treatment methods. The control group of maternal imports of carboprost tromethamine injection, the observation group of mothers given domestic card prostaglandin trometamol injection. The treatment effect of two groups of patients was compared. Results The blood loss in cesarean section, the amount of bleeding and total blood loss at 2 h after operation, the decrease of Hb and the decline of RBC at 24 h postpartum, the differences were not statistically significant (all P> 0.05 ). The average cost of treatment in the observation group was lower than that of the control group. The incidence of diarrhea, headache and nausea and vomiting were significantly higher in the observation group than in the control group (all P <0.05). Conclusion Deep intramuscular injection of domestic card prostaglandin trometamol injection can reduce postpartum hemorrhage, increase uterine contractility, the effect is obvious, safe, affordable, and maternal easier to accept.