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目的:探讨妊娠合并嗜铬细胞瘤的临床特点和诊治方法。方法:回顾性分析3例妊娠合并嗜铬细胞瘤患者的临床资料:平均28岁。临床表现为2例妊娠期阵发性高血压,1例妊娠期持续性高血压,3例均伴有心动过速。肿瘤直径平均4.9(3.1~6.0)cm。2例在行剖宫产后立即行肿瘤切除术,1例行剖宫产后二期行肿瘤切除术。结果:2例为肾上腺嗜铬细胞瘤,1例为肾上腺外嗜铬细胞瘤。3例均获得随访,随访时间为8~12个月,平均10个月,血压、心率正常,未见肿瘤复发。结论:妊娠合并嗜铬细胞瘤少见,多为良性,临床表现缺乏特异性,易误诊为妊娠高血压,对孕妇及胎儿危害极大,早期诊断、合理术前准备及手术治疗能够提高母婴生存率。
Objective: To investigate the clinical features and diagnosis and treatment of pheochromocytoma during pregnancy. Methods: The clinical data of 3 patients with pheochromocytoma during pregnancy were analyzed retrospectively: average 28 years old. Clinical manifestations of 2 cases of paroxysmal hypertension during pregnancy, 1 case of persistent hypertension during pregnancy, 3 cases were associated with tachycardia. Tumor diameter average 4.9 (3.1 ~ 6.0) cm. 2 cases underwent cesarean section immediately after cesarean section, and 1 case underwent cystectomy after cesarean section. Results: Two cases were adrenal pheochromocytoma and one case was extra-adrenal pheochromocytoma. Three patients were followed up for 8 to 12 months, an average of 10 months, blood pressure, heart rate was normal, no tumor recurrence. Conclusion: Pregnancy complicated with pheochromocytoma is rare, mostly benign, the clinical manifestations of the lack of specificity, easily misdiagnosed as pregnancy-induced hypertension, great harm to pregnant women and fetuses, early diagnosis, reasonable preoperative preparation and surgical treatment can improve maternal and infant survival rate.