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食管胃底静脉曲张破裂出血是肝硬化患者的严重并发症之一,发病急,病情重,病死率高达15％以上。我院于1996年1月至1998年9月用善得定(奥曲肽)加法莫替丁治疗食管胃底静脉曲张破裂出血39例,取得良好疗效,现报道如下。1 材料和方法1.1 材料 67例患者均为住院患者,临床表现为呕血和(或)黑便,均经胃镜证实肝硬化并食管胃底静脉破裂出血。随机分为两组:治疗组39例,其中男23例,女16例,年龄25～68岁。肝炎后肝硬化34例,酒精性肝硬化4例,布-卡综合征1例。对照组28例。两组在年龄、性别、病程及病情严重程度方面均具有可比性。
Esophageal and gastric variceal bleeding is one of the serious complications in patients with cirrhosis, acute onset, severe illness, case fatality rate as high as 15%. Our hospital from January 1996 to September 1998 with good set (octreotide) plus famotidine in the treatment of esophageal variceal bleeding in 39 cases, and achieved good results, are reported below. 1 Materials and Methods 1.1 Materials 67 patients were hospitalized patients, the clinical manifestations of hematemesis and / or melena, were confirmed by endoscopy of liver cirrhosis and esophageal and gastric variceal bleeding. Randomly divided into two groups: treatment group of 39 patients, including 23 males and 16 females, aged 25 to 68 years. Posthepatitis cirrhosis in 34 cases, alcoholic cirrhosis in 4 cases, Buka syndrome in 1 case. Control group of 28 cases. The two groups were comparable in terms of age, sex, duration of disease and severity of illness.