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目的:评价患有颅内动脉瘤(intracranial aneurysm,ICA)的眼底表现,以明确ICA和可辨别的视网膜改变的关系。方法:共分析了46位已经在神经外科诊断颅内动脉瘤患者的病历和眼部检查图像。所有的患者接受了包括荧光血管造影(fluorescein angiography,FAG)在内的眼科检查。此外,玻璃膜疣、黄斑变性、棉绒斑、硬性渗出、视网膜出血、动脉变细、动-静脉交叉征、臂-视网膜循环时间、动-静脉循环时间都进行了分析。ICA患者(组1)的检查结果和22例特发性视网膜前膜患者未患病眼(组2)的结果进行了比较。结果:两组患者的平均年龄分别为60.02岁(组1)和60.68岁(组2)(P=0.70)。高血压的患病率在两组中相似。两组中均未发现患视网膜大动脉瘤的患者。两组之间玻璃膜疣、黄斑变性、棉绒斑、硬性渗出、视网膜出血、动脉变细和动-静脉交叉征的情况无显著差异。平均臂-视网膜循环时间也未发现显著差异。结论:我们未发现有任何证据证明ICA患者FAG检查和眼底有特殊改变。
Objective: To evaluate the ocular manifestations of intracranial aneurysm (ICA) to determine the relationship between ICA and discernable retinal changes. METHODS: A total of 46 medical images and eye examinations of neurosurgical patients with intracranial aneurysms were analyzed. All patients underwent ophthalmic examinations including fluorescein angiography (FAG). In addition, drusen, macular degeneration, lint, hard exudation, retinal hemorrhage, arterial thinning, arteriovenous crossover syndrome, arm-retinal circulation time, arteriovenous circulation time were analyzed. The results of ICA patients (Group 1) were compared with those of 22 patients with idiopathic pre-retinal membranes who were not affected (Group 2). Results: The mean age of the two groups was 60.02 (group 1) and 60.68 (group 2), respectively (P = 0.70). The prevalence of hypertension was similar in both groups. No patient with retinal aneurysm was found in either group. There was no significant difference in the incidence of drusen, macular degeneration, lint, hard exudation, retinal hemorrhage, arterial thinning and arteriovenous crossover between the two groups. There was also no significant difference in mean arm-retinal circulation time. CONCLUSIONS: We have not found any evidence of specific changes in FAG examination and fundus in ICA patients.