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研究背景及临床问题青霉素过敏是最常报道的过敏情况,但是,大约有90%自我报告的青霉素过敏是不准确的。区别真正的过敏和其他的药物不良反应存在困难。患者常常会使用多种药物,尤其是住院患者。不准确的青霉素过敏报告可能会干扰抗菌药物的管理,带来显著的临床和经济影响,可造成抗菌药物耐药性、总的医疗成本、
Background and Clinical Problems Penicillin allergy is the most frequently reported allergy, however, about 90% of self-reported penicillin allergies are inaccurate. It is difficult to distinguish between true allergies and other adverse drug reactions. Patients often use multiple medications, especially inpatients. Inaccurate reports of penicillin allergy can interfere with the administration of antimicrobials, with significant clinical and economic implications that can lead to antimicrobial resistance, total medical costs,