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目的 :分析糖皮质激素在呼吸系统中的临床应用。方法 :回顾分析在我院接受糖皮质激素治疗的53例呼吸系统疾病患者资料,包括患者所患疾病、所用糖皮质激素,给药剂量及治疗结局等,以探讨糖皮质激素在呼吸系统疾病治疗中的临床价值。结果:本组采用糖皮质激素进行治疗的呼吸系统疾病主要包括急性呼吸窘迫综合症14(26.42%)例,危重哮喘8(15.09%)例,中重度哮喘急性发作17(32.08%)例,特发性间质性肺炎3(5.66%)例,慢性阻塞性肺疾病11(20.75%)例。53例罹患呼吸系统疾病患者经治疗后,除1例危重哮喘患者和1例慢性阻塞性肺疾病患者,转往其他医院接受治疗外,其他患者均痊愈,治愈率为96.23%。共有8例患者出现并发症,其中消化系统并发症4(7.55%)例,骨质疏松2(3.77%)例,感染1(1.89%)例,医源性肾上腺皮质功能亢进1(1.89%)例,并发症发生率为15.10%。结论 :糖皮质激素可有效治疗各类呼吸系统疾病,疗效确切,但为防止出现相关药物不良反应,临床医生应合理、规范的使用。
Objective: To analyze the clinical application of glucocorticoid in the respiratory system. Methods: A retrospective analysis of 53 patients with respiratory diseases receiving glucocorticoid therapy in our hospital, including the patient’s disease, glucocorticoid used, the dose and treatment outcome, to explore the glucocorticoid treatment of respiratory diseases In the clinical value. Results: The group of respiratory diseases treated with glucocorticoids included 14 (26.42%) cases of acute respiratory distress syndrome, 8 (15.09%) cases of critically ill asthma, 17 (32.08%) cases of moderate to severe asthma, 3 (5.66%) cases of interstitial pneumonia and 11 (20.75%) cases of chronic obstructive pulmonary disease. After treatment, 53 patients with respiratory diseases were treated except one case of critically ill asthmatic patients and one patient with chronic obstructive pulmonary disease. All patients were cured except for other hospitals. The cure rate was 96.23%. A total of 8 patients had complications, including 4 cases of digestive system complications (7.55%), 2 cases of osteoporosis (3.77%), 1 case of infection (1.89%) and 1 cases of iatrogenic hyperthyroidism (1.89% For example, the complication rate was 15.10%. Conclusion: Glucocorticoids can treat all kinds of respiratory diseases effectively and has a definite curative effect. However, in order to prevent the adverse reactions of related drugs, clinicians should use it rationally and normaly.