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目的比较不同剂量米非司酮治疗子宫肌瘤的疗效。方法选取2013年11月-2016年11月于医院就诊及治疗的子宫肌瘤患者30例,按照随机数字表法分为观察组和对照组各15例。对照组给予米非司酮25 mg,观察组患者给予米非司酮12.5 mg,对比2组患者的效果及不良反应发生情况。结果观察组总有效率为93.33%高于对照组的73.33%,差异有统计学的意义(P<0.05)。观察组患者的恶心呕吐、乏力、嗜睡的发生率均低于对照组,差异有统计学意义(P<0.05)。结论与应用25 mg剂量的米非司酮相比,应用12.5 mg剂量的米非司酮治疗子宫肌瘤患者的效果更佳。
Objective To compare the efficacy of different doses of mifepristone in the treatment of uterine fibroids. Methods Thirty patients with uterine fibroids who were treated and treated in hospital from November 2013 to November 2016 were selected and divided into observation group and control group according to random number table. The control group was given 25 mg of mifepristone, and the observation group was given 12.5 mg of mifepristone, comparing the effect of the two groups of patients and the incidence of adverse reactions. Results The total effective rate in observation group was 93.33%, which was higher than that in control group (73.33%), the difference was statistically significant (P <0.05). The incidence of nausea, vomiting, fatigue and drowsiness in the observation group were lower than those in the control group, with statistical significance (P <0.05). Conclusion Compared with the application of 25 mg dose of mifepristone, 12.5 mg dose of mifepristone in patients with uterine fibroids better.