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目的:分析35岁以上不孕妇女接受IVF-ET治疗的结局,以更好的指导临床。方法:回顾性分析2004年6月~2006年12月在我院接受IVF-ET助孕治疗的98例35岁以上妇女的临床资料。结果:根据年龄分为<40岁组和≥40岁组,两组患者在获卵数,受精率,种植率和生化妊娠率方面差异有统计学意义(P<0.05);根据基础FSH值分为≤12mIU/mL组,12~20mIU/mL组和20.1~32mIU/mL组,3组在周期取消率、Gn用量和获卵数方面差异有统计学意义(P<0.05)。结论:基础FSH与年龄相比,年龄更能预测IVF的成功率。没有理由把基础FSH值升高的高龄妇女排除在IVF治疗之外,通过IVF治疗她们仍然有受孕的可能。
Objective: To analyze the outcome of IVF-ET treatment for infertile women over the age of 35 to better guide the clinical practice. Methods: The clinical data of 98 women over the age of 35 who underwent IVF-ET in our hospital from June 2004 to December 2006 were analyzed retrospectively. Results: There were significant differences in the number of oocytes, fertilization rate, implantation rate and biochemical pregnancy rate between the two groups according to the age group <40 years old and ≥40 years old group (P <0.05). According to the basic FSH score (P <0.05). There were significant differences in cycle cancellation rate, Gn dosage and number of oocytes retrieved between the groups of ≤12mIU / mL, 12 ~ 20mIU / mL and 20.1 ~ 32mIU / mL. Conclusion: The basal FSH is more predictive of IVF success than age. There is no reason to exclude elderly women with elevated basal FSH values from IVF treatment and they may still have the possibility of conception through IVF.