神经纤维瘤病,又名Ven Reckling-hanson病,神经-皮肤综合征(neuro-cutancous syndrome)。1882年首次报告,其特点是周围神经或和颅神经发生多发性神经纤维瘤,以及皮肤出现棕黄斑、牛奶咖啡色素斑,这是遗传疾病,今调查二家系报告如下。一、谭家系①先证者(T.Ⅱ_4)谭××,女性,37岁,广东开平县人,父母非近亲,于1986年元月31日就诊,自诉:出世后发现全身皮肤生牛奶咖啡色素斑,10岁开 Neurofibromatosis, also known as Ven Reckling-hanson disease, neuro-cutancous syndrome. First reported in 1882, which is characterized by peripheral nerve or cranial nerve with multiple neurofibromas, and the skin appears brown spots, milk, coffee spots, which is a genetic disease, the survey of two families reported below. First, the Tan family ① Proof (T. Ⅱ_4) Tan × ×, female, 37 years old, Kaiping County, Guangdong Province, parents non-relatives, on January 31, 1986 Visit, private prosecution: found after birth, body milk, milk, coffee Pigmented spot, 10 years old