非甾体抗炎药物中阿司匹林易引起消化道出血,消炎痛及保太松毒副作用较大,因而限制了它们的临床应用。非那西汀因对肾脏毒性较强而被淘汰。六十年代初问世的新非甾体抗炎药——芳基丙酸类的共同特点是疗效强、毒性低、患者易于耐受。经国内外 Aspirin in non-steroidal anti-inflammatory drugs tends to cause gastrointestinal bleeding, indomethacin and side effects of preservatives, thus limiting their clinical application. Phenacetin due to the toxicity of the kidney was eliminated. The new non-steroidal anti-inflammatory drugs that came out in the early 1960s, the common feature of arylpropionic acids, are their efficacy, low toxicity and their tolerability. After at home and abroad