黄连素的新用途

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黄连素近年来广泛用于临床,除了在心血管疾病中的广泛应用外,在胃肠道疾病中的应用也日益增多。此外对Ⅱ型糖尿病、脓疱疮、慢性化脓性中耳炎、口疮等都有疗效。该药与其它药合用还可用于治疗癌症、中枢性呼吸衰竭、宫颈糜烂等疾病。据近2年的报道,黄连素又被发现了以下新用途: 1 用于治疗幽门变曲菌相关性胃炎,并与中药合用治疗慢性非特异性溃疡性结肠炎 李仁学报道,治疗组对28例幽门变曲菌(CP)相关性胃炎患者使用黄连素0.3g,胃舒平0.9g及普鲁苯辛15mg治疗,1日3次口服,对照组则使用胃舒平0.9g,普鲁苯辛15mg及甲氰咪胍0.2g治疗。均连续治疗3周,第4周进行胃镜复查。结果治疗组症状与体征明显好转,组织炎变基本消失,胃粘膜CP培养23例转阴,对照组症状与体征略有好转,炎变组织与 Berberine has been widely used in clinics in recent years. In addition to its wide application in cardiovascular diseases, its use in gastrointestinal diseases has also increased. In addition to type II diabetes, impetigo, chronic suppurative otitis media, aphthous ulcers and other effects. The drug can be used in combination with other drugs for the treatment of cancer, central respiratory failure, cervical erosion and other diseases. According to reports in the past two years, Berberine has been found in the following new applications: 1 For the treatment of Aspergillus pylorus-associated gastritis, and combined with traditional Chinese medicine treatment of chronic non-specific ulcerative colitis Li Ren, treatment group of 28 cases of pylorus Patients with CP-associated gastritis treated with berberine 0.3 g, Weishuping 0.9 g, and purubicin 15 mg were given orally three times a day. In the control group, Weishuping 0.9 g, prulene sulphite 15 mg and cinnamic iridin were used.胍 0.2g treatment. All patients were continuously treated for 3 weeks and the endoscopy was performed on the 4th week. Results The symptoms and signs of the treatment group improved obviously, the tissue inflammation disappeared, the CP of the gastric mucosa was negative in 23 cases, and the symptoms and signs of the control group improved slightly.
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