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目的 探讨冷冻肝切除对降低肝癌术后复发率和提高生存率的价值。方法 对84例原发性肝癌行冷冻肝切除,即对可切除肝癌,先用液氮( -196℃)冷冻,将癌块冷冻成冰球然后立即作常规根治性肝切除。术后定期随访。复发率和生存率用寿命表法统计。结果 术后恢复均顺利,无手术死亡,无严重并发症。冷冻肝切除后1、3、5年生存率分别为98 .7%、83 .9%和64 .0%。术后复发率分别为15. 1%、30 .1%和39. 0%。结论 冷冻肝切除是安全可行的,有可能降低肝癌术后复发率和提高生存率。冷冻肝切除与常规肝切除的远期疗效比较,尚需进一步观察。
Objective To investigate the value of frozen hepatectomy in reducing postoperative recurrence rate and increasing survival rate of hepatocellular carcinoma. Methods Eighty-four patients with primary liver cancer underwent cryo-resection, that is, resectable hepatocarcinoma. The tumor was first frozen in liquid nitrogen (-196 ℃) and frozen into ice hockey. Immediate radical hepatectomy was performed. Regular follow-up after surgery. The recurrence rate and survival rate with the life table method statistics. Results Postoperative recovery was smooth, no operative death, no serious complications. The 1, 3, 5 year survival rates after cryohepatectomy were 98.7%, 83.9% and 64.0% respectively. The recurrence rates were 15.1%, 30.1% and 39.0%, respectively. Conclusion Frozen hepatectomy is safe and feasible, which may reduce the postoperative recurrence rate and improve the survival rate of liver cancer. Frozen liver resection and conventional liver resection of the long-term efficacy, the need for further observation.